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1

Structure and signalling pathways of kinin receptors

Journal:

Year:

2003

Language:

english

File:

PDF, 106 KB

english, 2003

2

EGFR kinase domain mutations – functional impact and relevance for lung cancer therapy

Irmer, D, Funk, J O, Blaukat, A

Journal:

Year:

2007

Language:

english

File:

PDF, 272 KB

english, 2007

3

Therapeutic implications of p53 status on cancer cell fate following exposure to ionizing radiation and the DNA-PK inhibitor M3814

Sun, Qing, Guo, Yige, Liu, Xiaohong, Czauderna, Frank, Carr, Michael I., Zenke, Frank Tadashi, Blaukat, Andree, Vassilev, Lyubomir T

Journal:

Molecular Cancer Research

Year:

2019

Language:

english

File:

PDF, 6.13 MB

english, 2019

4

Prediction of active human dose: learnings from 20 years of Merck KGaA experience, illustrated by case studies

Peters, Sheila Annie, Petersson, Carl, Blaukat, Andree, Halle, Joern-Peter, Dolgos, Hugues

Journal:

Drug Discovery Today

Year:

2020

Language:

english

File:

PDF, 1.10 MB

english, 2020

5

xPharm: The Comprehensive Pharmacology Reference || Tyrosine Kinases

Blaukat, Andree

Year:

2007

File:

PDF, 114 KB

2007

6

Regulation of G Protein- Coupled Receptor Function and Expression Edited by Jeffrey L. Benovic

Andree Blaukat, Stefan Offermanns

Journal:

Year:

2001

Language:

english

File:

PDF, 49 KB

english, 2001

7

Synthesen von und mit Verbindungen R3ElHgElR3 (El = C, Si, Ge, Sn)

Prof. Dr. W. P. Neumann, U. Blaukat

Journal:

Angewandte Chemie

Year:

1969

Language:

german

File:

PDF, 218 KB

german, 1969

8

Preparation of the Compounds R3ElHgElR3 (El C, Si, Ge, Sn) and their Synthetic Applications

Prof. Dr. W. P. Neumann, Dipl.-Chem. U. Blaukat

Journal:

Angewandte Chemie International Edition

Year:

1969

Language:

english

File:

PDF, 244 KB

english, 1969

9

On the structure of the amino-terminal domain ED 1 of the B2 receptor

Said Abd Alla, Ursula Quitterer, Christian Schröder, Andree Blaukat, Angelika Horstmeyer, Jürgen Dedio, Helmut Reiländer, Werner Müller-Ester

Journal:

Immunopharmacology

Year:

1996

Language:

english

File:

PDF, 359 KB

english, 1996

10

On the structure of the amino-terminal domain ED1 of the B2 receptor

Said Abd Alla, Ursula Quitterer, Christian Schröder, Andree Blaukat, Angelika Horstmeyer, Jürgen Dedio, Helmut Reiländer, Werner Müller-Esterl

Journal:

Immunopharmacology

Year:

1996

Language:

english

File:

PDF, 292 KB

english, 1996

11

Synthesen mit verbindungen R3M-Hg-MR3 und (R2M-Hg)n(M = C, Si, Ge, Sn) : XI. Mercurierung und demercurierung mittels di-t-butylquecksilber, (CH3)3C-Hg-C(CH3)32

U. Blaukat, W.P. Neumann

Journal:

Journal of Organometallic Chemistry

Year:

1973

File:

PDF, 733 KB

1973

12

Synthesen mit verbindungen R3M-Hg-MR3 und (R2M-Hg)n (M=C, Si, Ge, Sn) XII. Darstellung von und umsetzungen mit verbindungen R3Sn-Hg-SnR3 und (R2Sn-Hg)n

U. Blaukat, W.P. Neumann

Journal:

Journal of Organometallic Chemistry

Year:

1973

File:

PDF, 732 KB

1973

13

Search for autoantibodies to the human bradykinin B2 receptor

Patrick Micke, Andree Blaukat, Werner Müller-Esterl

Journal:

Immunopharmacology

Year:

1997

Language:

english

File:

PDF, 163 KB

english, 1997

14

Inhibition of B2 receptor internalization delays its dephosphorylation

Andree Blaukat, Werner Müller-Esterl

Journal:

Immunopharmacology

Year:

1997

Language:

english

File:

PDF, 269 KB

english, 1997

15

Protein tyrosine kinase-mediated pathways in G protein-coupled receptor signaling

Ivan Dikic, Andree Blaukat

Journal:

Cell Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 1.45 MB

english, 1999

16

10.1038/35023515

Dikic, Ivan, Ivankovic-Dikic, Inga, Grönroos, Eva, Blaukat, Andree, Barth, Bernd-Uwe

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 338 KB

english, 2000

17

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

Tunaru, Sorin, Kero, Jukka, Schaub, Annette, Wufka, Christian, Blaukat, Andree, Pfeffer, Klaus, Offermanns, Stefan

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

18

Peptide mimotopes recognized by antibodies cetuximab and matuzumab induce a functionally equivalent anti-EGFR immune response

Hartmann, C, Müller, N, Blaukat, A, Koch, J, Benhar, I, Wels, W S

Journal:

Year:

2010

Language:

english

File:

PDF, 1007 KB

english, 2010

19

ACE inhibitor potentiation of bradykinin-induced venoconstriction

Markus Hecker, Andree Blaukat, Agnieszka T Bara, Werner Müller-Esterl, Rudi Busse

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 340 KB

english, 1997

20

Regulated and constitutive activation of specific signalling pathways by the human S1P5 receptor

Anke Niedernberg, Andree Blaukat, Torsten Schöneberg, Evi Kostenis

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 620 KB

english, 2003

21

Matuzumab Binding to EGFR Prevents the Conformational Rearrangement Required for Dimerization

Judith Schmiedel, Andree Blaukat, Shiqing Li, Thorsten Knöchel, Kathryn M. Ferguson

Journal:

Year:

2008

Language:

english

File:

PDF, 895 KB

english, 2008

22

Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63

Anke Niedernberg, Sorin Tunaru, Andree Blaukat, Ali Ardati, Evi Kostenis

Journal:

Cellular Signalling

Year:

2003

Language:

english

File:

PDF, 315 KB

english, 2003

23

Mechanisms for 2-methoxyestradiol-induced apoptosis of prostate cancer cells

Shizhong Bu, Andree Blaukat, Xin Fu, Nils-Erik Heldin, Maréne Landström

Journal:

Year:

2002

Language:

english

File:

PDF, 593 KB

english, 2002

24

Activation of mitogen-activated protein kinase by the bradykinin B2 receptor is independent of receptor phosphorylation and phosphorylation-triggered internalization

Andree Blaukat, Anne Pizard, Rabary M. Rajerison, François Alhenc-Gelas, Werner Müller-Esterl, Ivan Dikic

Journal:

Year:

1999

Language:

english

File:

PDF, 174 KB

english, 1999

25

Allosteric IGF-1R Inhibitors

Heinrich, Timo, Grädler, Ulrich, Böttcher, Henning, Blaukat, Andree, Shutes, Adam

Journal:

ACS Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 4.76 MB

english, 2010

26

216 Preclinical characterization of EMD 1214063 - a selective c-Met kinase inhibitor in clinical phase 1

O. Schadt, D. Dorsch, F. Stieber, A. Blaukat, F. Bladt, C. Fittschen, M. Meyring, M. Friese-Hamim, C. Knuehl, U. Graedler

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

27

xPharm: The Comprehensive Pharmacology Reference || Abl Kinase

Blaukat, Andree

Year:

2007

Language:

english

File:

PDF, 256 KB

english, 2007

28

Activation of Sphingosine Kinase by the Bradykinin B2 Receptor and Its Implication in Regulation of the ERK/MAP Kinase Pathway

Blaukat, Andree, Dikic, Ivan

Journal:

Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 140 KB

english, 2001

29

Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells

Humbert, Magali, Medová, Michaela, Aebersold, Daniel M., Blaukat, Andree, Bladt, Friedhelm, Fey, Martin F., Zimmer, Yitzhak, Tschan, Mario P.

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 547 KB

english, 2013

30

Phosphorylation and Regulation of a G Protein-Coupled Receptor by Protein Kinase CK2

Ignacio Torrecilla, Elizabeth J. Spragg, Benoit Poulin, Phillip J. McWilliams, Sharad C. Mistry, Andree Blaukat and Andrew B. Tobin

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 2.73 MB

english, 2007

31

Palmitoylation of the Human Bradykinin B 2 Receptor Influences Ligand Efficacy †

Pizard, Anne, Blaukat, Andree, Michineau, Stéphanie, Dikic, Ivan, Müller-Esterl, Werner, Alhenc-Gelas, François, Rajerison, Rabary M.

Journal:

Year:

2001

Language:

english

File:

PDF, 129 KB

english, 2001

32

Determination of Bradykinin B2 Receptor in Vivo Phosphorylation Sites and Their Role in Receptor Function

Blaukat, A., Pizard, A., Breit, A., Wernstedt, C., Alhenc-Gelas, F., Muller-Esterl, W., Dikic, I.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 931 KB

english, 2001

33

Overexpression and Functional Characterization of Kinin Receptors Reveal Subtype-Specific Phosphorylation †,‡

Blaukat, Andree, Herzer, Kerstin, Schroeder, Christian, Bachmann, Michael, Nash, Norman, Müller-Esterl, Werner

Journal:

Year:

1999

Language:

english

File:

PDF, 213 KB

english, 1999

34

The Novel ATP-Competitive Inhibitor of the MET Hepatocyte Growth Factor Receptor EMD1214063 Displays Inhibitory Activity against Selected MET-Mutated Variants

Medova, M., Pochon, B., Streit, B., Blank-Liss, W., Francica, P., Stroka, D., Keogh, A., Aebersold, D. M., Blaukat, A., Bladt, F., Zimmer, Y.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.82 MB

english, 2013

35

Mutation of Tyrosine in the Conserved NPXXY Sequence Leads to Constitutive Phosphorylation and Internalization, but Not Signaling, of the Human B2 Bradykinin Receptor

Kalatskaya, I., Schussler, S., Blaukat, A., Muller-Esterl, W., Jochum, M., Proud, D., Faussner, A.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 911 KB

english, 2004

36

Nephrocystin-4 Regulates Pyk2-induced Tyrosine Phosphorylation of Nephrocystin-1 to Control Targeting to Monocilia

Liebau, M. C., Hopker, K., Muller, R. U., Schmedding, I., Zank, S., Schairer, B., Fabretti, F., Hohne, M., Bartram, M. P., Dafinger, C., Hackl, M., Burst, V., Habbig, S., Zentgraf, H., Blaukat, A., Wa

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 3.64 MB

english, 2011

37

The Tyrosine Kinase Pyk2 Regulates Arf1 Activity by Phosphorylation and Inhibition of the Arf-GTPase-activating Protein ASAP1

Kruljac-Letunic, A., Moelleken, J., Kallin, A., Wieland, F., Blaukat, A.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 1016 KB

english, 2003

38

Ligand-induced Phosphorylation/Dephosphorylation of the Endogenous Bradykinin B2 Receptor from Human Fibroblasts

Blaukat, A., Alla, S. A., Lohse, M. J., Muller-Esterl, W.

Journal:

Journal of Biological Chemistry

Year:

1996

Language:

english

File:

PDF, 1.02 MB

english, 1996

39

Adaptor Proteins Grb2 and Crk Couple Pyk2 with Activation of Specific Mitogen-activated Protein Kinase Cascades

Blaukat, A., Ivankovic-Dikic, I., Gronroos, E., Dolfi, F., Tokiwa, G., Vuori, K., Dikic, I.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 881 KB

english, 1999

40

Angiotensin-Converting Enzyme Inhibitor Ramiprilat Interferes With the Sequestration of the B2 Kinin Receptor Within the Plasma Membrane of Native Endothelial Cells

Benzing, T., Fleming, I., Blaukat, A., Muller-Esterl, W., Busse, R.

Journal:

Year:

1999

Language:

english

File:

PDF, 443 KB

english, 1999

41

Downregulation of bradykinin B 2 receptor in human fibroblasts during prolonged agonist exposure

Blaukat, Andree, Micke, Patrick, Kalatskaya, Irina, Faussner, Alexander, Müller-Esterl, Werner

Journal:

AJP Heart and Circulatory Physiology

Year:

2003

Language:

english

File:

PDF, 207 KB

english, 2003

42

Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2

Torrecilla, I., Spragg, E. J., Poulin, B., McWilliams, P. J., Mistry, S. C., Blaukat, A., Tobin, A. B.

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 2.93 MB

english, 2007

43

Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors

Dorsch, Dieter, Schadt, Oliver, Stieber, Frank, Meyring, Michael, Grädler, Ulrich, Bladt, Friedhelm, Friese-Hamim, Manja, Knühl, Christine, Pehl, Ulrich, Blaukat, Andree

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 3.12 MB

english, 2015

44

EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors

Bladt, F., Faden, B., Friese-Hamim, M., Knuehl, C., Wilm, C., Fittschen, C., Gradler, U., Meyring, M., Dorsch, D., Jaehrling, F., Pehl, U., Stieber, F., Schadt, O., Blaukat, A.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

45

The C-terminal Tail of CRTH2 Is a Key Molecular Determinant That Constrains G i and Downstream Signaling Cascade Activation

Schroder, R., Merten, N., Mathiesen, J. M., Martini, L., Kruljac-Letunic, A., Krop, F., Blaukat, A., Fang, Y., Tran, E., Ulven, T., Drewke, C., Whistler, J., Pardo, L., Gomeza, J., Kostenis, E.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 759 KB

english, 2009

46

G Protein-Coupled Receptor-Mediated Mitogen-Activated Protein Kinase Activation through Cooperation of Galpha q and Galpha i Signals

Blaukat, A., Barac, A., Cross, M. J., Offermanns, S., Dikic, I.

Journal:

Molecular and Cellular Biology

Year:

2000

Language:

english

File:

PDF, 1.11 MB

english, 2000

47

The c-Met Inhibitor MSC2156119J Effectively Inhibits Tumor Growth in Liver Cancer Models

Bladt, Friedhelm, Friese-Hamim, Manja, Ihling, Christian, Wilm, Claudia, Blaukat, Andree

Journal:

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

48

KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells

Leiser, Dominic, Medová, Michaela, Mikami, Kei, Nisa, Lluís, Stroka, Deborah, Blaukat, Andree, Bladt, Friedhelm, Aebersold, Daniel M., Zimmer, Yitzhak

Journal:

Molecular Oncology

Year:

2015

Language:

english

File:

PDF, 3.19 MB

english, 2015

49

Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation

Mikami, K., Medova, M., Nisa, L., Francica, P., Gluck, A. A., Tschan, M. P., Blaukat, A., Bladt, F., Aebersold, D. M., Zimmer, Y.

Journal:

Molecular Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.82 MB

english, 2015

50

Depletion of FOXM1 via MET targeting underlies establishment of a DNA damage-induced senescence program in gastric cancer

Francica, P., Nisa, L., Aebersold, D. M., Langer, R., Bladt, F., Blaukat, A., Stroka, D., Rodriguez Martinez, M., Zimmer, Y., Medova, M.

Journal:

Clinical Cancer Research

Year:

2016

Language:

english

File:

PDF, 3.17 MB

english, 2016

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